Quantitative Imaging Biomarkers of NAFLD
Identifieur interne : 000102 ( Main/Exploration ); précédent : 000101; suivant : 000103Quantitative Imaging Biomarkers of NAFLD
Auteurs : Sonja Kinner [États-Unis, Allemagne] ; Scott B. Reeder [États-Unis] ; Takeshi Yokoo [États-Unis]Source :
- Digestive diseases and sciences [ 0163-2116 ] ; 2016.
Abstract
Conventional imaging modalities, including ultrasonography (US), computed tomography (CT), and magnetic resonance (MR), play an important role in the diagnosis and management of patients with nonalcoholic fatty liver disease (NAFLD) by allowing noninvasive diagnosis of hepatic steatosis. However, conventional imaging modalities are limited as biomarkers of NAFLD for various reasons. Multi-parametric quantitative MRI techniques overcome many of the shortcomings of conventional imaging and allow comprehensive and objective evaluation of NAFLD. MRI can provide unconfounded biomarkers of hepatic fat, iron, and fibrosis in a single examination—a virtual biopsy has become a clinical reality. In this article, we will review the utility and limitation of conventional US, CT, and MR imaging for the diagnosis NAFLD. Recent advances in imaging biomarkers of NAFLD are also discussed with an emphasis in multi-parametric quantitative MRI.
Url:
DOI: 10.1007/s10620-016-4037-1
PubMed: 26848588
PubMed Central: 4854639
Affiliations:
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Reeder</name><affiliation wicri:level="2"><nlm:aff id="A3">Department of Radiology, Medical Physics, Biomedical Engineering, Medicine, Emergency Medicine, University of Wisconsin, Madison, WI, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Radiology, Medical Physics, Biomedical Engineering, Medicine, Emergency Medicine, University of Wisconsin, Madison, WI</wicri:regionArea><placeName><region type="state">Wisconsin</region></placeName></affiliation></author><author><name sortKey="Yokoo, Takeshi" sort="Yokoo, Takeshi" uniqKey="Yokoo T" first="Takeshi" last="Yokoo">Takeshi Yokoo</name><affiliation wicri:level="2"><nlm:aff id="A4">Department of Radiology and Advanced Imaging Research Center, University of Texas Southwestern Medical Center, 2201 Inwood Road, NE2.210B, Dallas, TX 75390-9085, USA</nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Radiology and Advanced Imaging Research Center, University of Texas Southwestern Medical Center, 2201 Inwood Road, NE2.210B, Dallas, TX 75390-9085</wicri:regionArea><placeName><region type="state">Texas</region></placeName></affiliation></author></analytic><series><title level="j">Digestive diseases and sciences</title><idno type="ISSN">0163-2116</idno><idno type="eISSN">1573-2568</idno><imprint><date when="2016">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P1">Conventional imaging modalities, including ultrasonography (US), computed tomography (CT), and magnetic resonance (MR), play an important role in the diagnosis and management of patients with nonalcoholic fatty liver disease (NAFLD) by allowing noninvasive diagnosis of hepatic steatosis. However, conventional imaging modalities are limited as biomarkers of NAFLD for various reasons. Multi-parametric quantitative MRI techniques overcome many of the shortcomings of conventional imaging and allow comprehensive and objective evaluation of NAFLD. MRI can provide unconfounded biomarkers of hepatic fat, iron, and fibrosis in a single examination—a virtual biopsy has become a clinical reality. In this article, we will review the utility and limitation of conventional US, CT, and MR imaging for the diagnosis NAFLD. Recent advances in imaging biomarkers of NAFLD are also discussed with an emphasis in multi-parametric quantitative MRI.</p></div></front></TEI><affiliations><list><country><li>Allemagne</li><li>États-Unis</li></country><region><li>Texas</li><li>Wisconsin</li></region></list><tree><country name="États-Unis"><region name="Wisconsin"><name sortKey="Kinner, Sonja" sort="Kinner, Sonja" uniqKey="Kinner S" first="Sonja" last="Kinner">Sonja Kinner</name></region><name sortKey="Reeder, Scott B" sort="Reeder, Scott B" uniqKey="Reeder S" first="Scott B." last="Reeder">Scott B. Reeder</name><name sortKey="Yokoo, Takeshi" sort="Yokoo, Takeshi" uniqKey="Yokoo T" first="Takeshi" last="Yokoo">Takeshi Yokoo</name></country><country name="Allemagne"><noRegion><name sortKey="Kinner, Sonja" sort="Kinner, Sonja" uniqKey="Kinner S" first="Sonja" last="Kinner">Sonja Kinner</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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